Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 158
interventional 144
Observational 11
Registry 3

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Device 41
Procedure 25
Drug|placebo 21
Drug 20
Other 13
Biological|placebo 4
Biological 3
Drug|Procedure 3
Other|placebo 3
Device|Procedure 2
Other|Procedure 2
Biological|Procedure 1
Device|Drug 1
Device|Other 1
Drug|Other 1
Drug|placebo|Procedure 1
Other|Radiation 1
placebo|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 56
United Kingdom 17
China 8
NA 8
Canada 7
Denmark 6
Belgium 5
Cuba 4
Egypt 3
Germany 3
Korea, Republic of 3
Turkey 3
Brazil 2
India 2
Netherlands 2
Poland 2
Sweden 2
Austria 1
Belgium|Latvia|Lithuania|United Kingdom 1
France 1
Mexico 1
Poland|United Kingdom 1
Singapore 1
Spain 1
Taiwan 1
Thailand 1
United States|Denmark|France|Germany|Hungary|Italy|Latvia|Poland|Spain|United Kingdom 1
United States|Germany|Hungary|Spain 1

Sites per Study

Site_count Study_Count
1 123
2 4
3 5
4 1
5 2
7 3
9 2
10 1
21 1
40 1
47 1

Phase

Phase Study_Count
N/A 80
Phase 2 26
Phase 1 11
Phase 4 10
Phase 1/Phase 2 9
Phase 3 4
Phase 2/Phase 3 3
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 24
2 88
3 12
4 7
5 1
6 2
8 1
9 1
NA 8

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 10 4.0000 10.00000 15.00000 14.00000 17.00000 90.00 12.0
1st Qu. 10 17.7500 15.50000 20.00000 41.00000 38.50000 90.00 20.0
Median 10 26.0000 24.00000 35.00000 74.50000 60.00000 126.50 29.0
Mean 10 52.2875 34.36364 44.66667 77.38462 66.33333 173.25 37.9
3rd Qu. 10 60.0000 51.50000 43.00000 102.00000 91.00000 209.75 54.5
Max. 10 435.0000 70.00000 103.00000 175.00000 122.00000 350.00 90.0

Trial Group Type

group_type Group_Count
Experimental 125
Active Comparator 77
Placebo Comparator 45
Other 25
No Intervention 21
NA 8
Sham Comparator 5

Intervention Model

intervention_model Study_Count
Parallel Assignment 91
Single Group Assignment 46
Crossover Assignment 4
NA 2
Factorial Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 117
Prevention 17
Basic Science 4
Other 2
Supportive Care 2
NA 2

Observational Studies

Studies by Country

Country Study_Count
United States 3
Austria 1
Belgium 1
Denmark 1
Egypt 1
Italy 1
Korea, Republic of 1
Netherlands 1
Taiwan 1

Sites per Study

Site_count Study_Count
1 11

Enrollment Metrics

Measure Observational
Min 8.0000
1st Qu 20.0000
Median 35.0000
Mean 156.7273
3rd Qu 125.5000
Max 876.0000

Observation Model

observational_model Study_Count
Case-Control 4
Cohort 2
NA 2
Case-Only 1
Case Control 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 5
Retrospective 4
Cross-Sectional 2

Registries

Studies by Country

Country Study_Count
China 1
Finland 1
United States 1

Sites per Study

Site_count Study_Count
1 2
2 1

Enrollment Metrics

Measure Registries
Min 34.0000
1st Qu 117.0000
Median 200.0000
Mean 211.3333
3rd Qu 300.0000
Max 400.0000

Registry Model

observational_model Study_Count
Cohort 2
Case-Only 1

Time Perspective

time_perspective Study_Count
Prospective 2
Cross-Sectional 1

Follow-up

target_duration Study_Count
1 Year 1
10 Years 1
2 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03346668 Role of Neurogenic Inflammation and Topical 6% Gabapentin Therapy in Symptomatic Scarring Alopecia https://ClinicalTrials.gov/show/NCT03346668 Recruiting University of Minnesota 2020-08-01
NCT02985151 Interventional Study to Evaluate the Appearance of Surgical Scars After Laser Therapy https://ClinicalTrials.gov/show/NCT02985151 Active, not recruiting St. Louis University 2020-12-31
NCT03380845 Comparison of 1,550-nm Laser and Fractional Radiofrequency Microneedle for the Treatment of Acne Scars in Ethnic Skin https://ClinicalTrials.gov/show/NCT03380845 Completed Massachusetts General Hospital 2018-10-30
NCT02651298 CO2-laser Treatment for Caesarean Section Scars https://ClinicalTrials.gov/show/NCT02651298 Completed Bispebjerg Hospital 2015-01-31
NCT03352297 Nanofat in Post Burn Scars on the Face https://ClinicalTrials.gov/show/NCT03352297 Completed King Edward Medical University 2016-12-31
NCT03257514 Effect of Alpha Lipoic Acid on Uterine Scar Healing After Cesarean Section https://ClinicalTrials.gov/show/NCT03257514 Completed Ain Shams University 2018-01-01
NCT03197649 CO2 Laser Phototherapy for Management of Mature Burn Scars https://ClinicalTrials.gov/show/NCT03197649 Recruiting University of California, Davis 2022-05-31
NCT03181087 Safety of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars https://ClinicalTrials.gov/show/NCT03181087 Recruiting Maternal and Child Health Hospital of Foshan 2021-10-31
NCT03170596 Comparison Between Microneedling Daycare Procedure and Tazarotene 0.1% Gel Local Application in Acne Scarring https://ClinicalTrials.gov/show/NCT03170596 Completed Postgraduate Institute of Medical Education and Research 2018-02-28
NCT03078686 Biocellular-Cellular Regenerative Treatment Scaring Alopecia and Alopecia Areata https://ClinicalTrials.gov/show/NCT03078686 Recruiting Regeneris Medical 2025-01-22
NCT03057964 PDL and Fractional Photothermolysis for Postsurgical Scars https://ClinicalTrials.gov/show/NCT03057964 Enrolling by invitation Northwestern University 2021-12-31
NCT03039803 Impact of Double-layer Versus Single-layer Uterine Closure Suture in Cesarean Section on the Development of Postoperative Uterine Scar Deficiency https://ClinicalTrials.gov/show/NCT03039803 Recruiting Medical University of Vienna 2019-09-30
NCT02988622 Comparison of Lasers in the Treatment of Scars https://ClinicalTrials.gov/show/NCT02988622 Completed University of Iowa 2018-01-15
NCT02968459 Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars https://ClinicalTrials.gov/show/NCT02968459 Recruiting Maternal and Child Health Hospital of Foshan 2021-10-31
NCT02898350 Surgical Scar Treatment With the Pulsed Dye Laser in Combination With a CO2 Laser https://ClinicalTrials.gov/show/NCT02898350 Completed Syneron Medical 2016-02-29
NCT02886988 Early Postoperative Prevention and Treatment of Median Sternotomy Scars With Botulinum Toxin Type A Injection https://ClinicalTrials.gov/show/NCT02886988 Completed Xijing Hospital 2017-12-28
NCT02861248 Fractional Microplasma Radiofrequency Technology for Non-hypertrophic Post-burn Scars in Asians: A Prospective Study of 95 Patients https://ClinicalTrials.gov/show/NCT02861248 Completed Shanghai Jiao Tong University School of Medicine 2014-03-31
NCT02772289 Perinatal Tissue Mesenchyme Stem Cells in the Treatment for Caesarean Section Scars https://ClinicalTrials.gov/show/NCT02772289 Completed Maternal and Child Health Hospital of Foshan 2018-09-30
NCT02708628 The Efficacy of Extract of Allium Cepae, Allantoin and Heparin in Patients With Proven Scar Development https://ClinicalTrials.gov/show/NCT02708628 Completed Suleymaniye Birth And Women’s Health Education And Research Hospital 2016-04-30
NCT02707627 Laser Therapy for Pediatric Burn Scars https://ClinicalTrials.gov/show/NCT02707627 Recruiting The Hospital for Sick Children 2020-07-31
NCT02676115 Medipore Tape Study https://ClinicalTrials.gov/show/NCT02676115 Completed NYU Langone Health 2016-02-29
NCT02646917 SkinPen Efficacy on Acne Scars on the Face and/or Back https://ClinicalTrials.gov/show/NCT02646917 Completed Bellus Medical, LLC 2016-12-31
NCT02645773 Early Intervention With Non-ablative Fractional Laser to Reduce Cutaneous Scarring https://ClinicalTrials.gov/show/NCT02645773 Completed Bispebjerg Hospital 2015-12-31
NCT02643628 A Pilot Study to Evaluate the Safety and Effectiveness of Microneedling and Bellafill to Treat Facial Acne Scars https://ClinicalTrials.gov/show/NCT02643628 Completed Suneva Medical, Inc. 2017-06-05
NCT02630303 High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin https://ClinicalTrials.gov/show/NCT02630303 Completed VA Northern California Health Care System 2017-03-31
NCT02623829 Botulinum Toxin is a Potential Prophylactic Therapy for Minimizing Post-excisional Scarring (Allergan Botox Scar Study) https://ClinicalTrials.gov/show/NCT02623829 Completed Icahn School of Medicine at Mount Sinai 2019-03-01
NCT02472405 Multiplex Laser vs. PDL (Pulsed Dye Laser ) in the Treatment of Surgical Scars https://ClinicalTrials.gov/show/NCT02472405 Completed University of Miami 2016-11-30
NCT02397564 Treatment of Post-Surgical Scars With Traditional Ablative Er:YAG Versus Fractional Ablative Er:YAG https://ClinicalTrials.gov/show/NCT02397564 Completed University of Louisville 2016-07-31
NCT02396290 Clinical Effect of Platelet Rich Plasma Combined With Laser on Scar https://ClinicalTrials.gov/show/NCT02396290 Completed Seoul National University Hospital 2013-09-30
NCT02357095 UACE Followed by Uterine Suction Curettage for the Treatment of Caesarean Scar Pregnancy https://ClinicalTrials.gov/show/NCT02357095 Completed Maternal and Child Health Hospital of Hubei Province 2014-06-30
NCT02338388 Cesarean-scar Thickness and Closure Technique https://ClinicalTrials.gov/show/NCT02338388 Completed Charite University, Berlin, Germany 2014-04-30
NCT02340325 FS2 Safety and Tolerability Study in Healthy Volunteers https://ClinicalTrials.gov/show/NCT02340325 Completed British Columbia Professional Firefighters’ Burn and Wound Healing Laboratory 2016-01-31
NCT02216864 Effect of Multiple Subcisions on Rolling Acne Scars https://ClinicalTrials.gov/show/NCT02216864 Active, not recruiting Northwestern University 2020-12-31
NCT02174393 Microneedling Plus the Universal Peel For Acne Scarring https://ClinicalTrials.gov/show/NCT02174393 Completed Englewood Hospital and Medical Center 2015-12-31
NCT02120781 Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for the Treatment of Vocal Fold Scarring and Age-Related Dysphonia https://ClinicalTrials.gov/show/NCT02120781 Completed Fibrocell Technologies, Inc. 2016-04-30
NCT02115646 Fractionated Carbon Dioxide Laser and Burn Scar Contractures: Evaluation of Post-Treatment Scar Function and Appearance https://ClinicalTrials.gov/show/NCT02115646 Completed Massachusetts General Hospital 2017-01-31
NCT02103816 The Smartlipo Triplex 1440nm Wavelength Laser and the Sidelaze 800 Hand Piece for the Treatment of Facial Acne Scars https://ClinicalTrials.gov/show/NCT02103816 Completed Cynosure, Inc. 2015-02-28
NCT02103127 Evaluation of the Picosure 755nm Alexandrite Laser With Lens Array for the Treatment of Acne Scars https://ClinicalTrials.gov/show/NCT02103127 Completed Cynosure, Inc. 2015-05-31
NCT02088567 Amniotic Membrane in Total Knee Replacements to Reduce Scarring https://ClinicalTrials.gov/show/NCT02088567 Completed MiMedx Group, Inc. 2014-10-31
NCT02063243 Intralesional Cryotherapy With a Argon Gas Based Device for the Treatment of Keloid and Hypertrophic Scars https://ClinicalTrials.gov/show/NCT02063243 Completed VU University Medical Center 2012-01-31
NCT02050126 Caesarean Scar Revision With the UltraPulse https://ClinicalTrials.gov/show/NCT02050126 Completed Lumenis Ltd. 2016-01-31
NCT02033824 Amniotic Membrane in Decompressive Craniectomy to Reduce Scarring https://ClinicalTrials.gov/show/NCT02033824 Completed MiMedx Group, Inc. 2018-06-30
NCT02032641 Evaluation of Non-Ablative Laser for Treatment of Direct Brow Lift Scars https://ClinicalTrials.gov/show/NCT02032641 Completed University of Miami 2015-05-31
NCT02014298 Non Ablative Fractional Laser Treatment of Burn Scars https://ClinicalTrials.gov/show/NCT02014298 Completed Bispebjerg Hospital 2012-10-31
NCT01976260 A Pilot Study Testing Fractional Radiofrequency Versus Fractional Photothermolysis for the Treatment of Acne Scars https://ClinicalTrials.gov/show/NCT01976260 Active, not recruiting Northwestern University 2021-12-31
NCT01958450 Comparison of the Efficacy of Fractional Er:YAG Laser for Acne Scar https://ClinicalTrials.gov/show/NCT01958450 Completed Seoul National University Hospital 2013-05-31
NCT01910896 Effectiveness and Safety Study of Overnight Intensive Patch in Scars https://ClinicalTrials.gov/show/NCT01910896 Completed Merz Pharmaceuticals GmbH 2015-05-31
NCT01807455 An Open, Non-comparative Study of the Efficacy and Safety of Treatment of Acne Scars With Restylane Vital Lidocaine https://ClinicalTrials.gov/show/NCT01807455 Completed Q-Med AB 2014-12-31
NCT01789346 Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical Scars https://ClinicalTrials.gov/show/NCT01789346 Completed Cutera Inc. 2014-07-31
NCT01780077 Evaluation of Safety, PK, and Preliminary Effects on Scar Formation of Multiple Intradermal Administrations of RXI-109 https://ClinicalTrials.gov/show/NCT01780077 Completed RXi Pharmaceuticals, Corp. 2014-06-30
NCT01730339 Safety and Efficacy Study of PF-06473871 to Reduce Hypertrophic Scars From Recurring Post-Revision Surgery https://ClinicalTrials.gov/show/NCT01730339 Completed Pfizer 2014-10-31
NCT01711060 A Comparison of Balloon Catheter Versus Ocytocin for Cervical Ripening on Scarred Uterus With Unfavorable Cervix https://ClinicalTrials.gov/show/NCT01711060 Completed Poitiers University Hospital 2014-01-31
NCT01706848 Celotres for Improvement in Wound Healing and Resulting Scar Consequences Following Suturing of a Wound https://ClinicalTrials.gov/show/NCT01706848 Completed Halscion, Inc. 2014-05-31
NCT01696513 Effect of Subcision and Suction on Acne Scars https://ClinicalTrials.gov/show/NCT01696513 Active, not recruiting Northwestern University 2020-12-31
NCT01644435 A Pilot Study to Determine Safety & Efficacy of Autologous Human Platelet Lysate (HPL) in Treatment of Acne Scarring https://ClinicalTrials.gov/show/NCT01644435 Completed Kasiak Research Pvt. Ltd. 2012-10-31
NCT01640912 Evaluation of the Safety, Pharmacokinetics, and Preliminary Effect on Scar Formation by RXI-109 https://ClinicalTrials.gov/show/NCT01640912 Completed RXi Pharmaceuticals, Corp. 2014-04-30
NCT01619917 The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars https://ClinicalTrials.gov/show/NCT01619917 Active, not recruiting University of Manitoba 2020-06-30
NCT01504061 Mederma to Reduce Appearance of Post Surgical Scars https://ClinicalTrials.gov/show/NCT01504061 Completed Merz North America, Inc. 2012-06-30
NCT01494922 Safety and Efficacy of EXC 001 in Subjects Who Have Participated in Prior Studies of EXC 001 https://ClinicalTrials.gov/show/NCT01494922 Completed Pfizer 2013-09-30
NCT01488240 The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars https://ClinicalTrials.gov/show/NCT01488240 Active, not recruiting University of Manitoba 2020-06-30
NCT01438125 MF-4181 for the Reduction of Scars Secondary to Abdominoplasty or Laparoscopy/Laparotomy Gynecologic Procedures https://ClinicalTrials.gov/show/NCT01438125 Completed Halscion, Inc. 2011-05-31
NCT01413789 Measurement and Comparison of the Occlusive and Hydrating Capacity of Three Silicone Gels and One Gel Cream https://ClinicalTrials.gov/show/NCT01413789 Completed University Hospital, Ghent 2012-07-31
NCT01410175 Comparison of the Impact of Electric Scalpels Versus Cold Scalpels https://ClinicalTrials.gov/show/NCT01410175 Completed Barretos Cancer Hospital 2012-07-31
NCT01358838 Ablative 10600 nm Fractional Laser Therapy for the Treatment of Scars https://ClinicalTrials.gov/show/NCT01358838 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2011-12-31
NCT01346969 Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery https://ClinicalTrials.gov/show/NCT01346969 Completed Pfizer 2012-04-30
NCT04389164 Tissue-engineered Skin Graft Repair of Autologous Scar Dermal Scaffolds https://ClinicalTrials.gov/show/NCT04389164 Recruiting First Affiliated Hospital, Sun Yat-Sen University 2025-12-31
NCT04379219 Surgery Alone Versus Methotrexate Before Surgery in Cesarean Scar Pregnancy https://ClinicalTrials.gov/show/NCT04379219 Recruiting Mansoura University 2020-08-31
NCT04186273 Clinical Safety and Scar Prevention Study of a Topical Antifibrotic Compound FS2. https://ClinicalTrials.gov/show/NCT04186273 Recruiting University of British Columbia 2021-02-01
NCT04169490 “A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities” https://ClinicalTrials.gov/show/NCT04169490 Recruiting The Center for Clinical and Cosmetic Research 2021-01-27
NCT04168125 Use of Tilapia Skin for Palate Repair and Protection After Graft Removal https://ClinicalTrials.gov/show/NCT04168125 Recruiting University of Sao Paulo 2020-04-23
NCT04066946 Study for the Effects of Microcurrent Therapy on the Prevention and Healing of Brachioplasty Scars https://ClinicalTrials.gov/show/NCT04066946 Enrolling by invitation Organisation for Burns, Scar Aftercare and Research 2021-04-30
NCT04034615 The Long-term Effect of Perinatal Tissue Mesenchyme Stem Cells in the Treatment for Caesarean Section Scars https://ClinicalTrials.gov/show/NCT04034615 Recruiting Maternal and Child Health Hospital of Foshan 2021-12-01
NCT03982862 Botulinum Toxins Intralesional Injection for Scar Pain https://ClinicalTrials.gov/show/NCT03982862 Recruiting Kaohsiung Medical University 2019-06-30
NCT03936309 A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section https://ClinicalTrials.gov/show/NCT03936309 Recruiting 375th Medical Group, Scott Air Force Base 2024-05-31
NCT03915847 Evaluation of Cesarean Scar After Three Different Uterine Closure Technis https://ClinicalTrials.gov/show/NCT03915847 Completed Ataturk University 2020-04-16
NCT03901417 Comparison of 1550nm Fractional Laser Alone Versus in Combination With Microneedling for the Treatment of Acne Scars https://ClinicalTrials.gov/show/NCT03901417 Active, not recruiting Massachusetts General Hospital 2020-06-30
NCT03887208 Therapy of Scars and Cutis Laxa With Autologous Adipose Derived Mesenchymal Stem Cells https://ClinicalTrials.gov/show/NCT03887208 Completed Medical University of Warsaw 2019-01-31
NCT03880058 Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance https://ClinicalTrials.gov/show/NCT03880058 Active, not recruiting Scarless Laboratories, Inc. 2020-12-30
NCT03850925 Comparison of Picosecond Pulsed Nd:YAG Laser and Fractional Laser for the Treatment of Acne Scars https://ClinicalTrials.gov/show/NCT03850925 Recruiting Dongtan Sacred Heart Hospital 2020-04-30
NCT03842644 Postoperative Skin Surface Tension Relaxing in Prevention of Facial Surgical Skin Scarring https://ClinicalTrials.gov/show/NCT03842644 Recruiting Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University 2020-09-01
NCT03795116 Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention https://ClinicalTrials.gov/show/NCT03795116 Active, not recruiting State University of New York - Downstate Medical Center 2020-05-31
NCT03782038 Study to Evaluate the Efficacy of a Micro Coring Device for the Treatment of Scars of the Cytrellis Micro-Coring Device for the Treatment of Scars https://ClinicalTrials.gov/show/NCT03782038 Recruiting Cytrellis Biosystems, Inc. 2019-09-17
NCT03767153 Clinical Evaluation of Fractional Radiofrequency for the Treatment of Acne Scarring https://ClinicalTrials.gov/show/NCT03767153 Active, not recruiting Venus Concept 2019-10-05
NCT03664505 Evaluation of the Product Properties of Individualized 3D-compression Garments to Treat Scars https://ClinicalTrials.gov/show/NCT03664505 Completed University of Schleswig-Holstein 2018-11-09
NCT03644433 Impact of Uterine Closure Techniques on the Cesarean Scar Thickness After Repeated Cesarean Section https://ClinicalTrials.gov/show/NCT03644433 Recruiting Ataturk University 2019-04-30
NCT03627650 Fat Grafting in Skin-grafted Deep Burn Scars https://ClinicalTrials.gov/show/NCT03627650 Completed University Hospital, Ghent 2016-09-10
NCT03601247 Silicone Gel for Postsurgical Scars of the Eyelid https://ClinicalTrials.gov/show/NCT03601247 Recruiting Montefiore Medical Center 2020-08-01
NCT03569267 A Study to Evaluate Safety and PK Profiles of OLX10010 in Healthy Subjects https://ClinicalTrials.gov/show/NCT03569267 Completed Olix Pharmaceuticals, Inc. 2019-06-27
NCT03514615 A Trial to Assess the Safety and Efficacy of Topical Salbutamol in Healthy Volunteers. https://ClinicalTrials.gov/show/NCT03514615 Completed University Hospitals, Leicester 2018-07-20
NCT03469830 The Development and Application of “Scar-care” Padding on Management of Hypertrophic Scar https://ClinicalTrials.gov/show/NCT03469830 Completed The Hong Kong Polytechnic University 2016-11-01
NCT03467724 Treatment of Surgical Scars Following Breast Augmentation, Abdominoplasty or Face Lift https://ClinicalTrials.gov/show/NCT03467724 Recruiting Venus Concept 2020-03-31
NCT03433664 Carbon Dioxide Laser Treatment in Burn-related Scarring https://ClinicalTrials.gov/show/NCT03433664 Completed The University of Western Australia 2015-01-16
NCT04456127 CO2 Laser Revision for Burn Related Donor Site Scars https://ClinicalTrials.gov/show/NCT04456127 Recruiting Medstar Health Research Institute 2021-07-01
NCT03416660 Efficacy of Different Densities of Fractional Carbon Dioxide in Treatment of Post Burn Scars https://ClinicalTrials.gov/show/NCT03416660 Completed Cairo University 2017-12-01
NCT01264588 The Effects of Topical Calcium Glycerophosphate on Surgical Wound Healing and Residual Scarring https://ClinicalTrials.gov/show/NCT01264588 Completed AkPharma Inc. 2010-10-31
NCT01217567 Subcuticular Suture Versus Staples for Closure of the Skin After Caesarean Section. https://ClinicalTrials.gov/show/NCT01217567 Completed Holbaek Sygehus 2011-07-31
NCT01201525 Pulsed Dye Laser Treatment of Recent Surgical Scars https://ClinicalTrials.gov/show/NCT01201525 Completed University Hospital, Ghent 2011-08-31
NCT01176448 Laser Resurfacing Versus Dermabrasion for Scar Revision https://ClinicalTrials.gov/show/NCT01176448 Completed University of Minnesota 2010-08-31
NCT01112371 Contractubex Treatment in Scars After Abdominal Caesarean Section https://ClinicalTrials.gov/show/NCT01112371 Completed Merz Pharmaceuticals GmbH 2012-02-29
NCT01091181 The Effect of Hysterotomy Technique on the Rate of Large Defects in the Hysterotomy Scar https://ClinicalTrials.gov/show/NCT01091181 Completed Region Skane 2016-12-01
NCT01056211 1540nm Non Ablative Fractional Laser Treatment of Scars https://ClinicalTrials.gov/show/NCT01056211 Completed University Hospital, Ghent 2013-08-31
NCT01038297 Safety and Efficacy Study of Different Dose Levels of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty https://ClinicalTrials.gov/show/NCT01038297 Completed Pfizer 2010-07-31
NCT01037413 Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery https://ClinicalTrials.gov/show/NCT01037413 Completed Pfizer 2010-12-31
NCT01018589 Cicatrix Cream in Post Surgical Scars and Epidermic Burn https://ClinicalTrials.gov/show/NCT01018589 Completed Catalysis SL 2010-12-31
NCT01018212 Cicatrix Cream in Cutaneous Groves https://ClinicalTrials.gov/show/NCT01018212 Completed Catalysis SL 2010-12-31
NCT00993005 CICATRIX in the Treatment of Hypertrophic Scars and Keloids Scars https://ClinicalTrials.gov/show/NCT00993005 Completed Catalysis SL 2010-12-31
NCT00991367 CICATRIX in the Treatment of Recent Post-surgical Scars https://ClinicalTrials.gov/show/NCT00991367 Completed Catalysis SL 2010-12-31
NCT00984854 Investigation Into the Safety of Intradermal Juvidex (M6P) Administered to Wounds of Healthy Subjects https://ClinicalTrials.gov/show/NCT00984854 Completed Renovo 2004-07-31
NCT00984646 Investigation Into the Scar Reduction Potential of Prevascar (Interleukin-10) https://ClinicalTrials.gov/show/NCT00984646 Completed Renovo 2006-11-30
NCT00984581 Safety and Efficacy Study of Avotermin (Juvista) in Female Subjects https://ClinicalTrials.gov/show/NCT00984581 Completed Renovo 2004-08-31
NCT00984503 Investigation of the Accelerated Healing and Anti-scarring Potential of Avotermin (Juvista) in Split Skin Graft Donor Sites https://ClinicalTrials.gov/show/NCT00984503 Completed Renovo 2006-01-31
NCT00984386 Investigation of the Efficacy of Zesteem in Accelerating Early Wound Healing https://ClinicalTrials.gov/show/NCT00984386 Completed Renovo 2005-04-30
NCT00978367 Investigation of the Safety, Dosing Frequency and Anti-Scarring Potential of Two Concentrations of Intradermal Avotermin (Juvista) https://ClinicalTrials.gov/show/NCT00978367 Completed Renovo 2002-11-30
NCT00978302 Safety Study of Repeated, Escalating Doses of Intradermal Avotermin (Juvista) https://ClinicalTrials.gov/show/NCT00978302 Completed Renovo 2001-08-31
NCT00977951 Genomic Changes Associated With the Use of Intradermal Avotermin (Juvista) in Small Wounds in Healthy Male Subjects https://ClinicalTrials.gov/show/NCT00977951 Completed Renovo 2003-09-30
NCT00984516 Investigation Into the Safety and Scar-improvement Efficacy of Intradermal Juvidex Dosed Once or Three Times https://ClinicalTrials.gov/show/NCT00984516 Completed Renovo 2006-01-31
NCT00974870 A Pilot Study Testing the Efficacy of a Needling Device for the Treatment of Acne Scars https://ClinicalTrials.gov/show/NCT00974870 Completed Northwestern University 2010-07-31
NCT00970671 Treatment of Surgical Scars Using the Pulsed Dye Laser https://ClinicalTrials.gov/show/NCT00970671 Completed University of California, San Diego 2010-12-31
NCT00969215 Burn Scar Appearance After Treatment With Fractional Carbon Dioxide (CO2) Laser https://ClinicalTrials.gov/show/NCT00969215 Completed Moy-Fincher Medical Group 2010-09-30
NCT00852280 Effects of Pulsed-Dyed Laser on Scar Formation https://ClinicalTrials.gov/show/NCT00852280 Completed Shriners Hospitals for Children 2011-01-31
NCT00847925 Safety and Efficacy of RN1001(Avotermin) in Healthy Male Subjects https://ClinicalTrials.gov/show/NCT00847925 Completed Renovo 2003-09-30
NCT00847795 Efficacy and Safety of Intradermal RN1001 (Avotermin) in Elderly Subjects. https://ClinicalTrials.gov/show/NCT00847795 Completed Renovo 2003-06-30
NCT04420442 Scar Resection and Reconstruction With Integra and Split Skin Grafts in Patients With Non-Suicidal Self-Inflicted Scars https://ClinicalTrials.gov/show/NCT04420442 Recruiting Berufsgenossenschaftliche Unfallklinik Ludwigshafen 2022-11-30
NCT01221922 Laser Treatment of Acne Scars in Fitzpatrick Skin Types III-VI https://ClinicalTrials.gov/show/NCT01221922 Completed Cynosure, Inc. 2012-01-31
NCT00811577 A Phase 2a Study to Evaluate the Safety and Efficacy of AZX100 in Trocar Sites of Arthroscopic Shoulder Surgery Patients https://ClinicalTrials.gov/show/NCT00811577 Completed Capstone Therapeutics 2010-12-31
NCT01932359 Rapidly Absorbable Versus Non-absorbable Sutures for Mohs Surgery Repair on the Face: a Randomized Controlled Split-scar Study https://ClinicalTrials.gov/show/NCT01932359 Completed University of British Columbia 2014-03-31
NCT03036306 Dose Ranging Study to Evaluate the Safety and Tolerability of SCX-001 Cream in Healthy Volunteers With Induced Dermal Incisions https://ClinicalTrials.gov/show/NCT03036306 Completed ScarX Corp 2017-10-02
NCT01981330 Pilot Study of Stem Cell Treatment of Patients With Vocal Fold Scarring https://ClinicalTrials.gov/show/NCT01981330 Completed Karolinska University Hospital 2020-02-24
NCT03821324 Clinical Evaluation of Fractional Radiofrequency for the Treatment Acne Scarring https://ClinicalTrials.gov/show/NCT03821324 Active, not recruiting Venus Concept 2019-11-01
NCT00754247 A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scars https://ClinicalTrials.gov/show/NCT00754247 Completed University of Miami 2008-02-29
NCT00742443 Juvista in Scar Revision Surgery of Disfiguring Scars https://ClinicalTrials.gov/show/NCT00742443 Completed Renovo 2011-01-31
NCT00651820 Effect of Collagenase on Healing and Scarring https://ClinicalTrials.gov/show/NCT00651820 Completed Healthpoint 2009-11-30
NCT00642642 Safety and Efficacy Study of Autologous Fibroblasts in the Treatment of Severe Facial Acne Scarring https://ClinicalTrials.gov/show/NCT00642642 Completed Fibrocell Technologies, Inc. 2009-03-31
NCT00629811 Improvement in Scar Appearance Following Injection of Avotermin (Juvista) Into Skin Incisions Made in Healthy Men and Women https://ClinicalTrials.gov/show/NCT00629811 Completed Renovo 2007-08-31
NCT00627536 Scar-Improvement Efficacy and Safety of a Single Intradermal Injection of Avotermin (Juvista) Administered Following Full-Thickness Skin Incisions https://ClinicalTrials.gov/show/NCT00627536 Completed Renovo 2007-03-31
NCT00607685 5FU vs 5FU With Viscoelastic Formulation for the Prevention of Scarring Post-trabeculectomy https://ClinicalTrials.gov/show/NCT00607685 Completed Singapore National Eye Centre 2010-01-31
NCT00594581 Anti-Scarring Efficacy and Safety of Intradermal Juvista (Avotermin) in Healthy Males https://ClinicalTrials.gov/show/NCT00594581 Completed Renovo NA
NCT00585286 Fractional Resurfacing Device for Treatment of Acne Scarring https://ClinicalTrials.gov/show/NCT00585286 Completed University of California, Irvine 2008-07-31
NCT00510055 Treatment of Acne Scarring With a Novel Procedure Combination https://ClinicalTrials.gov/show/NCT00510055 Completed Northwestern University 2009-07-31
NCT00482144 Study of the Effects of the Pulsed-dye Laser at 585nm and 595nm to Treat Post-operative Scars on Suture-removal Day https://ClinicalTrials.gov/show/NCT00482144 Completed University of Miami 2008-01-31
NCT00450775 Evaluation of the Efficacy, Tolerability, and Patient Acceptance of Dermatix Q for the Prevention and Management of Scars https://ClinicalTrials.gov/show/NCT00450775 Completed Innovative Medical 2008-03-31
NCT00436449 RN1001(Avotermin) in Scar Improvement Following Breast Augmentation https://ClinicalTrials.gov/show/NCT00436449 Completed Renovo 2007-10-31
NCT00430326 Juvista (Avotermin) in Scars Following Varicose Vein Removal https://ClinicalTrials.gov/show/NCT00430326 Completed Renovo 2009-01-31
NCT00261963 The Effect of UV-Irradiation on Cutaneous Cicatrices https://ClinicalTrials.gov/show/NCT00261963 Completed Bispebjerg Hospital NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03395015 Efficacy of Maxillo-facial Treatment on Cleft Lip and Palate Patients Faces: Aesthetic Considerations https://ClinicalTrials.gov/show/NCT03395015 Completed Fondazione Policlinico Universitario Agostino Gemelli IRCCS 2017-07-20
NCT02352623 Quality of Life and Surgical Late Effects of Melanoma Treatment https://ClinicalTrials.gov/show/NCT02352623 Completed Herlev Hospital 2016-02-29
NCT02115789 Perceptions of Aesthetic Outcomes of Zigzag and Linear Scars https://ClinicalTrials.gov/show/NCT02115789 Completed University of California, Davis 2013-06-30
NCT01994616 Prospective Evaluation of the Use of Intralesional Cryotherapy for Treatment of Keloid and Hypertrophic Scars https://ClinicalTrials.gov/show/NCT01994616 Completed VU University Medical Center 2011-01-31
NCT01970761 Autologous Fat Graft Alleviate Scar Pain https://ClinicalTrials.gov/show/NCT01970761 Completed Kaohsiung Medical University Chung-Ho Memorial Hospital 2013-01-31
NCT01688063 Skin Elasticity Measurements of the Face and Surgical Scars Stratified by Age and Skin Type https://ClinicalTrials.gov/show/NCT01688063 Active, not recruiting Northwestern University 2020-12-31
NCT04187586 Effect of Extracorporeal Shock Wave Therapy for Burn Scar Charateristics https://ClinicalTrials.gov/show/NCT04187586 Completed Hangang Sacred Heart Hospital 2019-12-12
NCT03971968 Observational Study for the Long-Term Effects of a Dermal Substitute on Patients With Facial Burns. https://ClinicalTrials.gov/show/NCT03971968 Completed Universitair Ziekenhuis Brussel 2019-02-14
NCT01040104 Prospective Clinical Trials on Skin Wound Healing in Young and Aged Individuals https://ClinicalTrials.gov/show/NCT01040104 Completed Medical University of Vienna 2011-07-31
NCT03780699 Hysteroscopic Evaluation of Cesarean Scar Defect https://ClinicalTrials.gov/show/NCT03780699 Recruiting Ain Shams University 2019-04-01
NCT00691769 Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia https://ClinicalTrials.gov/show/NCT00691769 Completed Wake Forest University Health Sciences 2012-11-26

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03044782 Barriers to Care and QOL for CCCA Patients https://ClinicalTrials.gov/show/NCT03044782 Completed Northwestern University 2017-09-30
NCT02717312 Prevalence, Risk Factors and Consequences Related to Cesarean Scar Defect (Defect in Cesarean Scar) https://ClinicalTrials.gov/show/NCT02717312 Active, not recruiting Tampere University Hospital 2017-09-30
NCT04096677 Effects of Hysteroscopy and Transvaginal Surgery on Reproductive Prognosis in Patients With Post Cesarean Scar Defect https://ClinicalTrials.gov/show/NCT04096677 Recruiting First Affiliated Hospital, Sun Yat-Sen University 2019-09-30